Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Uncovering novel MHC alleles from RNA-Seq data: expanding the spectrum of MHC class I alleles in sheep.

BMC genomic data - 3 Jan 2023

Buitkamp Johannes

Abstract excerpt

BACKGROUND: Major histocompatibility complex (MHC) class I glycoproteins present selected peptides or antigens to CD8 + T cells that control the cytotoxic immune response. The MHC class I genes are among the most polymorphic loci in the vertebrate genome, with more than twenty thousand alleles known in humans. In sheep, only a very small number of alleles have been described to date, making the development of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Biological Evolution
Share to RNA-Seq

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 36597020
DOI: 10.1186/s12863-022-01102-5
PMCID: PMC9809118

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Uncovering novel MHC alleles from RNA-Seq data: expanding the spectrum of MHC class I alleles in sheep.PMID 36597020Read ↗

Uncovering novel MHC alleles from RNA-Seq data: Expanding the spectrum of MHC class I alleles in sheepSemantic proximity Read ↗

Large scale transcriptional analysis of MHC class I haplotype diversity in sheep.Semantic proximity Read ↗

Newly identified variability of the antigen binding site coding sequences of the equine major histocompatibility complex class I and class II genes.Semantic proximity Read ↗

Rapid identification of bovine MHCI haplotypes in genetically divergent cattle populations using next-generation sequencing.Semantic proximity Read ↗

A single nomenclature and associated database for alleles at the major histocompatibility complex class II DRB1 locus of sheep.Semantic proximity Read ↗

A novel RNAseq-assisted method for MHC class I genotyping in a non-model species applied to a lethal vaccination-induced alloimmune disease.Semantic proximity Read ↗

Canine major histocompatibility complex class I (MHC-I) diversity landscapeSemantic proximity Read ↗

MHCtools 1.5: Analysis of MHC Sequencing Data in R.Semantic proximity Read ↗

HLAProfiler utilizes k-mer profiles to improve HLA calling accuracy for rare and common alleles in RNA-seq data.Semantic proximity Read ↗

An Illumina approach to MHC typing of Atlantic salmon.Semantic proximity Read ↗

Complete sequences of six Major Histocompatibility Complex haplotypes, including all the major <i>MHC class II</i> structuresSemantic proximity Read ↗

Complete sequences of six major histocompatibility complex haplotypes, including all the major MHC class II structures.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.