Article

Uncovering novel MHC alleles from RNA-Seq data: Expanding the spectrum of MHC class I alleles in sheep

2022-05-25

Abstract excerpt

<h4>Background: </h4> Major histocompatibility complex (MHC) class I glycoproteins present selected peptides or antigens to CD8+ T cells that control the cytotoxic immune response. The MHC class I genes are among the most polymorphic loci in the vertebrate genome, with more than 20tsd alleles known in humans. In sheep, only a very small number of alleles have been described to date, making the development of typin...

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Literature Corpus work: 6d9528f3-4455-56e8-81a6-b3c35d34ff2a
DOI: 10.21203/rs.3.rs-1291063/v1

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