Article

Current genomic deep learning models display decreased performance in cell type specific accessible regions

2024-07-10

Abstract excerpt

<h4>Background: </h4> A number of deep learning models have been developed to predict epigenetic features such as chromatin accessibility from DNA sequence. Model evaluations commonly report performance genome-wide; however, cis regulatory elements (CREs), which play critical roles in gene regulation, make up only a small fraction of the genome. Furthermore, cell type specific CREs contain a large proportion of c...

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Literature Corpus work: ea887d8b-b235-5370-b7dd-abd98a8cd081
DOI: 10.1101/2024.07.05.602265

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