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Comprehensive identification of fetal cis-regulatory elements in the human genome by single-cell multi-omics analysis

2021-11-03

Abstract excerpt

The regulatory programs driving early organogenesis in human is complex and still poorly understood. We performed parallel profiling of gene expression and chromatin accessibility to 28 human fetal tissue samples representing 14 organs in the first trimester. Collectively, we have generated 415,793 single-cell profiles. By integration analysis of transcriptome and chromatin accessibility, we detected 225 distinct...

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Literature Corpus work
02fec41d-a6d8-561d-88cd-707a992e382a
DOI
10.1101/2021.11.02.466852
Open publication

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Comprehensive identification of fetal cis-regulatory elements in the human genome by single-cell multi-omics analysisDOI 10.1101/2021.11.02.466852
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