Article

Polygenic scores via penalized regression on summary statistics

2016-06-10

Abstract excerpt

Polygenic scores (PGS) summarize the genetic contribution of a person’s genotype to a disease or phenotype. They can be used to group participants into different risk categories for diseases, and are also used as covariates in epidemiological analyses. A number of possible ways of calculating polygenic scores have been proposed, and recently there is much interest in methods that incorporate information available...

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Literature Corpus work: 5fd8878a-909d-5abc-a514-2e0dbbb7c83c
DOI: 10.1101/058214

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