Article

A systematic, unbiased mapping of CD8 <sup>+</sup> and CD4 <sup>+</sup> T cell epitopes in Yellow Fever vaccinees

2020-03-29

Abstract excerpt

1. Examining CD8 + and CD4 + T cell responses after primary Yellow Fever vaccination in a cohort of 210 volunteers, we have identified and tetramer-validated 92 CD8 + and 50 CD4 + T cell epitopes, many inducing strong and prevalent (i.e. immunodominant) T cell responses. Restricted by 40 and 14 HLA-class I and II allotypes, respectively, these responses have wide population coverage and might be of considerabl...

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Literature Corpus work: 5fd02e47-a94d-5076-ae81-6443ecb5b1d0
DOI: 10.1101/2020.03.28.012468

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