Article

Comprehensive analysis of antiviral adaptive immunity formation and reactivation down to single-cell level

2019-10-25

Abstract excerpt

The diverse repertoire of T-cell receptors (TCR) plays a key role in the adaptive immune response to infections. Previous studies show that secondary responses to the yellow fever vaccine — the model for acute infection in humans — are weaker than primary ones, but only quantitative measurements can describe the concentration changes and lineage fates for distinct T-cell clones in vivo over time. Using TCR alpha...

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Literature Corpus work: 28df7a62-27ab-5514-8eb9-362e1d1acbb2
DOI: 10.1101/820134

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