Article
Identification of Novel Yellow Fever Class II Epitopes in YF-17D Vaccinees.
Viruses - 12 Nov 2020
Mateus Jose, Grifoni Alba, Voic Hannah, Angelo Michael A, Phillips Elizabeth, Mallal Simon, Sidney John, Sette Alessandro, Weiskopf Daniela
Abstract excerpt
Yellow fever virus (YFV) is a mosquito-borne member of the genus flavivirus, including other important human-pathogenic viruses, such as dengue, Japanese encephalitis, and Zika. Herein, we report identifying 129 YFV Class II epitopes in donors vaccinated with the live attenuated YFV vaccine (YFV-17D). A total of 1156 peptides predicted to bind 17 different common HLA-DRB1 allelic variants were tested using IFNγ...
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