Article

Quantification of the effect of site-specific histone acetylation on chromatin transcription rate

2019-06-22

Abstract excerpt

<h4>ABSTRACT</h4> Eukaryotic transcription is epigenetically regulated by chromatin structure and post-translational modifications (PTMs). For example, lysine acetylation in histone H4 is correlated with activation of RNA polymerase I-, II-, and III-driven transcription from chromatin templates, which requires prior chromatin remodeling. However, quantitative understanding of the contribution of particular PTM st...

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Literature Corpus work: 5f70fd4e-6e0f-55c4-bde1-2dd11a9d22b2
DOI: 10.1101/679944

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