Article

Cell-cycle-dependent repression of histone gene transcription by histone H4

2024-12-24

Abstract excerpt

In all eukaryotes DNA replication is coupled to histone synthesis to coordinate chromatin packaging of the genome. Canonical histone genes coalesce in the nucleus into the Histone Locus Body (HLB), where gene transcription and 3’ mRNA processing occurs. Both histone gene transcription and mRNA stability are reduced when DNA replication is inhibited, implying that the Histone Locus Body senses the rate of DNA synth...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: eeb87cd8-8ce3-5d43-99b9-c6245a5fae85
DOI: 10.1101/2024.12.23.630206

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cell-cycle-dependent repression of histone gene transcription by histone H4DOI 10.1101/2024.12.23.630206Read

Histone supply regulates S phase timing and cell cycle progression.Semantic proximity Read

Enrichment of HP1a on Drosophila chromosome 4 genes creates an alternate chromatin structure critical for regulation in this heterochromatic domain.Semantic proximity Read

Histone variants in development and diseases.Semantic proximity Read

Cell type- and chromosome-specific chromatin landscapes and DNA replication programs of <i>Drosophila</i> testis tumor stem cell-like cellsSemantic proximity Read

Histone variants and transcription regulation.Semantic proximity Read

Histone variants and epigenetics.Semantic proximity Read

Histone variants--ancient wrap artists of the epigenome.Semantic proximity Read

Histone variant H2A.Z facilitates DNA replication.Semantic proximity Read

Differentiating Drosophila female germ cells initiate Polycomb silencing by altering PRC2 samplingSemantic proximity Read

<i>In vivo</i> tissue-specific chromatin profiling in <i>Drosophila melanogaster</i> using GFP-tagged nucleiSemantic proximity Read

Allelic reprogramming of the histone modification H3K4me3 in early mammalian development.Semantic proximity Read

ZC3H4 restricts non-coding transcription in human cellsSemantic proximity Read