Article

Capturing <i>in vivo</i> RNA transcriptional dynamics from the malaria parasite <i>P. falciparum</i>

2017-01-11

Abstract excerpt

<h4>SUMMARY:</h4> To capture the transcriptional dynamics within proliferating cells, methods to differentiate nascent transcription from pre-existing mRNAs are desired. One approach is to label newly synthesized mRNA transcripts in vivo through the incorporation of modified pyrimidines. However, the human malaria parasite, Plasmodium falciparum , is incapable of pyrimidine salvage for mRNA biogenesis. To captu...

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Literature Corpus work: 1803a39a-24fa-5c19-a6ea-21c6c5d253b7
DOI: 10.1101/099549

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