Article

ATAC and SAGA histone acetyltransferase modules facilitate transcription factor binding to nucleosomes in an acetylation independent manner

2023-10-27

Abstract excerpt

<h4>SUMMARY</h4> Transcription initiation involves the coordination of multiple events, starting with activators binding specific DNA target sequences, which recruits transcription co-activators to open chromatin and enable binding of general transcription factors and RNA polymerase II to promoters. Two key human transcriptional coactivator complexes, ATAC (ADA-Two-A-Containing) and SAGA (Spt-Ada-Gcn5-acetyltrans...

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Literature Corpus work: 1f810864-1fb2-58d9-b5c6-51f782392d1f
DOI: 10.1101/2023.10.27.564358

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