Article

Cell-specific regulatory circuits connect genetic variation to disease susceptibility

2026-06-03

Abstract excerpt

Genome-wide association studies have identified thousands of variants associated with immune-related diseases, yet most lie in non-coding regions, complicating mechanistic interpretation. Regulatory quantitative trait loci (QTLs), such as expression QTLs (eQTLs) and chromatin accessibility QTLs (caQTLs), offer a powerful framework for prioritization and interpretation of these disease-associated genetic variants....

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Literature Corpus work: 5f0cdbbd-546d-5c6f-9726-849eb54d48de
DOI: 10.64898/2026.06.01.729215

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