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Single-Cell Transcriptomic Analysis Reveals Molecular Diversity of Human Oligodendrocyte Progenitor Cells

2020-10-08

Abstract excerpt

<h4>ABSTRACT</h4> Injury and loss of oligodendrocytes can cause demyelinating diseases such as multiple sclerosis. To improve our understanding of oligodendrocyte development, which could facilitate development of remyelination-based treatment strategies, we performed single-cell-transcriptomic-analysis of developing human oligodendrocyte-precursor-cells (hOPCs). We engineered knock-in hESC-reporter lines in whic...

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Literature Corpus work
5f0238f7-769e-5057-b39e-c9fb24a435c5
DOI
10.1101/2020.10.07.328971
Open publication

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Single-Cell Transcriptomic Analysis Reveals Molecular Diversity of Human Oligodendrocyte Progenitor CellsDOI 10.1101/2020.10.07.328971
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