Article

Developmental landscape of human forebrain at a single-cell level unveils early waves of oligodendrogenesis

2021-07-22

Abstract excerpt

Oligodendrogenesis in the human central nervous system has been mainly observed at the second trimester of gestation, a much later developmental stage compared to mouse. Here we characterize the transcriptomic neural diversity in the human forebrain at post conceptual weeks (PCW) 8 to 10, using single-cell RNA-Seq. We find evidence of the emergence of a first wave of oligodendrocyte lineage cells as early as PCW 8...

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Literature Corpus work: 087a3da1-9f05-5495-a50e-b12f9689135c
DOI: 10.1101/2021.07.22.453317

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