Article

Single Cell RNAseq to identify subpopulations of glial progenitors in iPSC-derived oligodendroglial lineage cultures

2024-12-20

Abstract excerpt

<h4>Summary</h4> Cellular heterogeneity is a common issue in differentiation protocols of oligodendrocytes (OLs) from human induced pluripotent stem cells. Our previous work described a novel method to generate OLs and highlighted the presence of glial progenitors. Here, we unravel the glial heterogeneity and characterize the response of isolated subpopulations to differentiation. This study provides a novel tool...

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Literature Corpus work: 12322bd5-e48c-5c46-b14f-1a979fd6766f
DOI: 10.1101/2024.12.18.629204

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