Article

Towards Digital Quantification of Ploidy from Pan-Cancer Digital Pathology Slides using Deep Learning

2024-08-20

Abstract excerpt

<h4>ABSTRACT</h4> Abnormal DNA ploidy, found in numerous cancers, is increasingly being recognized as a contributor in driving chromosomal instability, genome evolution, and the heterogeneity that fuels cancer cell progression. Furthermore, it has been linked with poor prognosis of cancer patients. While next-generation sequencing can be used to approximate tumor ploidy, it has a high error rate for near-euploid...

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Literature Corpus work: 5ef1a9c1-9279-5d88-b525-7b3343dc2157
DOI: 10.1101/2024.08.19.608555

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