Article

Early Electrophysiological Aberrations in the Hippocampus of the TgF344-AD Rat Model as a Potential Biomarker for Alzheimer’s Disease Prognosis

2022-07-03

Abstract excerpt

The hippocampus is thought to guide navigation and has an essential contribution to learning and memory. Hippocampus is one of the brain regions impaired in Alzheimer’s disease (AD), a neurodegenerative disease with progressive memory impairments and cognitive decline. Although successful treatments for AD are still not available, developing new strategies to detect AD at early stages before clinical manifestation...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5ee0eebb-fb3d-5d08-bd8d-cb21c61a74ed
DOI: 10.1101/2022.07.01.498373

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Early Electrophysiological Aberrations in the Hippocampus of the TgF344-AD Rat Model as a Potential Biomarker for Alzheimer’s Disease PrognosisDOI 10.1101/2022.07.01.498373Read

Insights From TgF344-AD, a Double Transgenic Rat Model in Alzheimer’s Disease ResearchSemantic proximity Read

Resting-state functional dynamics alterations relate to plasma amyloid markers and explain memory impairments in the TgF344-AD model of Alzheimer’s diseaseSemantic proximity Read

High Frequency Oscillations (>250Hz) Outnumber Interictal Spikes in Preclinical Studies of Alzheimer’s DiseaseSemantic proximity Read

Precuneus Failures in Subjects of the PSEN1 E280A Family at Risk of Developing Alzheimer's Disease Detected Using Quantitative Electroencephalography.Semantic proximity Read

Sound-evoked auditory neurophysiological signals are a window into prodromal functional differences in a preclinical model of Alzheimer′s DiseaseSemantic proximity Read

Early hippocampal hyperexcitability in PS2APP mice: role of mutant PS2 and APP.Semantic proximity Read

Tau in cerebrospinal fluid induces neuronal hyperexcitability and alters hippocampal theta oscillationsSemantic proximity Read

Quantitative electroencephalography (qEEG), apolipoprotein A-I (APOA-I), and apolipoprotein epsilon 4 (APOE ɛ4) alleles for the diagnosis of mild cognitive impairment and Alzheimer's disease.Semantic proximity Read

High-frequency oscillations arise through distinct mechanisms in models of α- synucleinopathy and channelopathy-induced epilepsySemantic proximity Read

The neurophysiology of healthy and pathological aging: A comprehensive systematic reviewSemantic proximity Read

Neural oscillations during cognitive processes in an App knock-in mouse model of Alzheimer's disease pathology.Semantic proximity Read

Behavioral Phenotype in the TgF344-AD Rat Model of Alzheimer’s DiseaseSemantic proximity Read