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An entropy-based diagnostic framework for characterizing methylation state dynamics during preimplantation development

2026-08-26

Abstract excerpt

DNA methylation undergoes predictable changes with age, and preimplantation embryos are known to undergo global epigenetic reprogramming. However, the specific fate of age associated methylation signatures during early development has not been systematically quantified. Using published human sperm age associated differentially methylated regions (DMRs) as a feature space, we integrated single cell methylome and tr...

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Literature Corpus work
5e6e274b-6ab7-5f55-ab85-dcfe8f16f72c
DOI
10.64898/2026.08.25.746714
Open publication

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An entropy-based diagnostic framework for characterizing methylation state dynamics during preimplantation developmentDOI 10.64898/2026.08.25.746714
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