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DNA methylation changes during preimplantation development reveal inter-species differences and reprogramming events at imprinted genes

11 May 2020

Abstract excerpt

Preimplantation embryos experience profound resetting of epigenetic information inherited from the gametes. Genome-wide analysis at single-base resolution has shown similarities but also species differences between human and mouse preimplantation embryos in DNA methylation patterns and reprogramming. Here, we have extended such analysis to two key livestock species, the pig and the cow. We generated genome-wide...

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Share to Epigenetics and DNA Methylation
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PMID: 32393379
DOI: 10.1186/s13148-020-00857-x

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