Article

Soluble SorCS1 binds the insulin receptor to enhance insulin sensitivity

2022-01-28

Abstract excerpt

<title>Abstract</title> <p>Type 2 diabetes has reached endemic proportions and is a substantial burden for the affected patients and the society. Along with lifestyle factors, a number of genetic loci predisposing to type 2 diabetes have been identified, including SORCS1 that encodes the transmembrane receptor SorCS1. The ectodomain of SorCS1 (sol-SorCS1) is shed from plasma membranes but the biological function...

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Literature Corpus work: 5e5c6640-9e4d-5ac8-b663-ad50db2c37e5
DOI: 10.21203/rs.3.rs-1299440/v1

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