Back to search

Article

Atlas of genetic effects in human microglia transcriptome across brain regions, aging and disease pathologies

2020-10-28

Abstract excerpt

Microglial cells have emerged as potential key players in brain aging and pathology. To capture the heterogeneity of microglia across ages and regions, and to understand how genetic risk for neurological and psychiatric brain disorders is related to microglial function, large transcriptome studies are essential. Here, we describe the transcriptome analysis of 255 primary human microglia samples isolated at autopsy...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
5e2342ca-36ec-53ce-98f4-03461d03ecbf
DOI
10.1101/2020.10.27.356113
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Atlas of genetic effects in human microglia transcriptome across brain regions, aging and disease pathologiesDOI 10.1101/2020.10.27.356113
Select a neighboring publication to make it the new centre.