Article

Intercellular adhesion molecule-1 protects against adipose tissue inflammation and insulin resistance but promotes liver inflammation and hepatic fibrosis in mice

2025-05-01

Abstract excerpt

<h4>ABSTRACT</h4> Metabolic dysfunction associated steatotic liver disease (MASLD) presents a growing global health problem with a range of manifestations, including steatosis, steatohepatitis, and cirrhosis. It is strongly associated with obesity, disease progression being promoted not only by hepatic leukocyte accumulation but also by inflammatory signals from adipose tissue and an altered gut microbiome. To de...

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Literature Corpus work: 5c7e3ccb-b5b2-5198-a489-a6313ea48675
DOI: 10.1101/2025.04.28.650968

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