Article
Impact of CD1d deficiency on metabolism.
PloS one - 1 Jan 2011
Kotas Maya E, Lee Hui-Young, Gillum Matthew P, Annicelli Charles, Guigni Blas A, Shulman Gerald I, Medzhitov Ruslan
Abstract excerpt
Invariant natural killer T cells (iNKTs) are innate-like T cells that are highly concentrated in the liver and recognize lipids presented on the MHC-like molecule CD1d. Although capable of a myriad of responses, few essential functions have been described for iNKTs. Among the many cell types of the immune system implicated in metabolic control and disease, iNKTs seem ideally poised for such a role, yet little has...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
