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Article

Obesity activates toll-like receptor-mediated proinflammatory signaling cascades in the adipose tissue of mice.

The Journal of nutritional biochemistry - 1 Feb 2012

Kim Seung-Jin, Choi Youngshim, Choi Youn-Hee, Park Taesun

Abstract excerpt

Obesity is characterized by low-grade and chronic inflammation, a phenomenon explained with a new term, metaflammation. Recent studies suggest that adipocytes may play an important role in the physiological regulation of immune responses in fat deposits via toll-like receptor (TLR) signaling cascades. This study investigates the role of the visceral as well as subcutaneous adipose tissues in the development of...

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Share to Adipose Tissue
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mice, Obese

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Source

Identifiers

PMID: 21414767
DOI: 10.1016/j.jnutbio.2010.10.012

Genes

TLR1
TLR4
TLR5
TLR8
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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