Article
Availability of an inflammatory macrophage niche drives phenotypic and functional alterations in Kupffer cells
2024-04-28
Abstract excerpt
Inflammatory signals lead to recruitment of circulating monocytes and induce their differentiation into disease-associated macrophages 1–3 . Therefore, whether blocking inflammatory monocytes can mitigate disease progression is being actively evaluated 4 . Here, we employed multiple lineage tracing models and confirmed that monocyte-derived macrophages (mo-macs) are the major population of liver metastasis-assoc...
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Identifiers and source
- Literature Corpus work
- 5c61c7fc-d930-51ab-abdc-975720b3bb05
- DOI
- 10.1101/2024.04.23.590829