Article

Repopulating Kupffer Cells Originate Directly from Hematopoietic Stem Cells

2020-07-31

Abstract excerpt

Kupffer cells (KCs) originate from yolk sac progenitors before birth. Throughout adulthood, they self-maintain independently from the input of circulating monocytes (MOs) at stead state, and are replenished within 2 weeks after having been depleted, but the origin of repopulating KCs in adult remains unclear. The current paradigm dictates that repopulating KCs originate from preexisting KCs or monocytes, but there...

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Literature Corpus work: 6c3a1508-4569-5d4f-99b5-45be8c5b57fd
DOI: 10.1101/2020.07.31.230649

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