Article
Understanding the Heterogeneity of Resident Liver Macrophages.
Frontiers in immunology - 1 Jan 2019
Blériot Camille, Ginhoux Florent
Abstract excerpt
Resident tissue macrophages (RTMs) are cells with a high functional plasticity assuming pleiotropic roles in their tissue of residence, from clearance of dead cells and metabolic sensing in steady state to cytokine production and tissue repair during inflammation. The liver has long been considered as only populated by Kupffer cells (KCs), a macrophage population assumed to be in charge of all of these functions....
Topics
- Animals
- Humans
- Liver
- Macrophages
- Phenotype
- Transcriptome