Article

Repopulating Kupffer Cells Originate Directly from Hematopoietic Stem Cells

2021-11-09

Abstract excerpt

<title>Abstract</title> <p>Kupffer cells (KCs) originate from yolk sac progenitors before birth, but the origin of repopulating KCs in adult remains unclear. In current study, we firstly traced the fate of preexisting KCs and that of monocytic cells with tissue-resident macrophage-specific and monocytic cell-specific fate mapping mouse models, respectively, and found no evidences that repopulating KCs originate f...

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Literature Corpus work: 25c06710-4ed7-5445-bca9-dff562f4b182
DOI: 10.21203/rs.3.rs-1034533/v1

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