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Article

Immunological imprinting shapes the specificity of human antibody responses against SARS-CoV-2 variants

2024-01-09

Abstract excerpt

<h4>Summary</h4> The spike glycoprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) continues to accumulate substitutions, leading to breakthrough infections of vaccinated individuals and prompting the development of updated booster vaccines. Here, we determined the specificity and functionality of antibody and B cell responses following exposure to BA.5 and XBB variants in individuals who rece...

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Identifiers and source

Literature Corpus work
5c56e106-0196-5c79-a6b5-6b500a649dca
DOI
10.1101/2024.01.08.24301002
Open publication

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Immunological imprinting shapes the specificity of human antibody responses against SARS-CoV-2 variantsDOI 10.1101/2024.01.08.24301002
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