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Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape

2022-09-30

Abstract excerpt

<h4>SUMMARY</h4> Memory B cells (MBCs) generate rapid antibody responses upon secondary encounter with a pathogen. Here, we investigated the kinetics, avidity and cross-reactivity of serum antibodies and MBCs in 155 SARS-CoV-2 infected and vaccinated individuals over a 16-month timeframe. SARS-CoV-2-specific MBCs and serum antibodies reached steady-state titers with comparable kinetics in infected and vaccinated...

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Literature Corpus work
72fb381c-4515-5a93-a358-f6b9fd94f979
DOI
10.1101/2022.09.30.509852
Open publication

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Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escapeDOI 10.1101/2022.09.30.509852
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