Article

Differential antibody dynamics to SARS-CoV-2 infection and vaccination

2021-09-10

Abstract excerpt

<h4>ABSTRACT</h4> Optimal immune responses furnish long-lasting (durable) antibodies protective across dynamically mutating viral variants (broad). To assess robustness of mRNA vaccine-induced immunity, we compared antibody durability and breadth after SARS-CoV-2 infection and vaccination. While vaccination delivered robust initial virus-specific antibodies with some cross-variant coverage, pre-variant SARS-CoV-2...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b6026e8d-6175-5c28-a0fb-7bc902f562ff
DOI: 10.1101/2021.09.09.459504

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Differential antibody dynamics to SARS-CoV-2 infection and vaccinationDOI 10.1101/2021.09.09.459504Read

Humoral waning kinetics against SARS-CoV-2 is dictated by disease severity and vaccine platformSemantic proximity Read

Quick COVID-19 Healers Sustain Anti-SARS-CoV-2 Antibody Production.Semantic proximity Read

SARS-CoV-2 induced B cells generate an anticipatory memory against new virus variants and re-engage in COVID-19 vaccine responsesSemantic proximity Read

Antibody responses to SARS-CoV-2 variants LP.8.1, LF.7.1, NB.1.8.1, XFG and BA.3.2 following KP.2 monovalent mRNA vaccinationSemantic proximity Read

Repeated COVID-19 vaccine boosters elicit variant-specific memory B cells in humansSemantic proximity Read

Serial vaccination expands and refines human CD4 <sup>+</sup> T cell memorySemantic proximity Read

Sustained Humoral Activation through self-amplifying mRNA Vaccination Enhances Longitudinal Antibody Function in a Phase III TrialSemantic proximity Read

Naturally enhanced neutralizing breadth to SARS-CoV-2 after one yearSemantic proximity Read

Immunological imprinting shapes the specificity of human antibody responses against SARS-CoV-2 variantsSemantic proximity Read

Antibody escape, the risk of serotype formation, and rapid immune waning: modeling the implications of SARS-CoV-2 immune evasionSemantic proximity Read

Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escapeSemantic proximity Read

Immunological imprinting shapes the cross-reactive antibody responses to the KP.2 and LP.8.1 vaccine dosesSemantic proximity Read