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Article

Prolonged evolution of the human B cell response to SARS-CoV-2 infection

12 Feb 2021

Abstract excerpt

A comprehensive understanding of the kinetics and evolution of the human B cell response to SARS-CoV-2 infection will facilitate the development of next-generation vaccines and therapies. Here, we longitudinally profiled this response in mild and severe COVID-19 patients over a period of five months. Serum neutralizing antibody (nAb) responses waned rapidly but spike (S)-specific IgG + memory B cells (MBCs)...

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Identifiers

PMID: 33622975
DOI: 10.1126/sciimmunol.abg6916

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