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Complement Factor H and its <i>C. elegans</i> homolog regulate IFT52/OSM-6 and CNG channel localization in sensory neurons

2025-10-13

Abstract excerpt

<h4>ABSTRACT</h4> Age-related macular degeneration (AMD), the leading cause of blindness in the elderly, is characterized by progressive degeneration of retinal photoreceptors. Current disease models propose AMD pathogenesis is a consequence of cytolytic damage and tissue inflammation that result from defective repression of alternative complement pathway activity by complement factor H (CFH). However, recent stu...

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Literature Corpus work
5c4eb048-6e24-5f98-b78e-4b77c53a2ec2
DOI
10.1101/2025.10.10.681644
Open publication

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Complement Factor H and its <i>C. elegans</i> homolog regulate IFT52/OSM-6 and CNG channel localization in sensory neuronsDOI 10.1101/2025.10.10.681644
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