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Article

Cfh genotype interacts with dietary glycemic index to modulate age-related macular degeneration-like features in mice.

Investigative ophthalmology & visual science - 23 Jan 2014

Rowan Sheldon, Weikel Karen, Chang Min-Lee, Nagel Barbara A, Thinschmidt Jeffrey S, Carey Amanda, Grant Maria B, Fliesler Steven J, Smith Donald, Taylor Allen

Abstract excerpt

PURPOSE: Age-related macular degeneration (AMD) is a leading cause of visual impairment worldwide. Genetics and diet contribute to the relative risk for developing AMD, but their interactions are poorly understood. Genetic variations in Complement Factor H (CFH), and dietary glycemic index (GI) are major risk factors for AMD. We explored the effects of GI on development of early AMD-like features and changes to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24370827
DOI: 10.1167/iovs.13-12413
PMCID: PMC3901416

Genes

RPE
CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cfh genotype interacts with dietary glycemic index to modulate age-related macular degeneration-like features in mice.PMID 24370827Read ↗

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