Article
Mechanobiological Specialization of Choroid Plexus Macrophages Defined by Titin Expression
2026-01-21
Abstract excerpt
<h4>Summary</h4> Functioning both as the site of cerebrospinal fluid production and as an interface between the peripheral circulation and the central nervous system, the choroid plexus (ChP) modulates the gating of immune cells and signals from the periphery as they pass from the blood into cerebrospinal fluid. We generated a single-nucleus and spatial transcriptomic atlas of the adult human ChP, in donors with...
Topics
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- Memory and Neural Mechanisms
- Alzheimer's disease research and treatments
- Cerebrospinal fluid and hydrocephalus
- Genetic Neurodegenerative Diseases
- Macrophage Migration Inhibitory Factor
- Neuroinflammation and Neurodegeneration Mechanisms
- Retinal Diseases and Treatments
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- 25ee58b0-0958-5219-b119-922aedf958b3
- DOI
- 10.64898/2026.01.20.700716
