Article

Association between mosaic loss of chromosome Y and pulmonary fibrosis susceptibility and severity

2024-05-30

Abstract excerpt

<h4>Background: </h4> Pulmonary fibrosis (PF) is a rare lung disease with diverse pathogenesis and multiple interconnected underlying biological mechanisms. Mosaic loss of chromosome Y (mLOY) is one of the most common forms of acquired chromosome abnormality in men, which has been reported to be associated with increased risk of various chronic progressive diseases including fibrotic diseases. However, the exact r...

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Literature Corpus work: 5c16469e-84f7-5b5a-8ecf-88685fb0d9d2
DOI: 10.1101/2024.05.25.595885

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