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Predictors of mosaic chromosome Y loss and associations with mortality in the UK Biobank

13 Aug 2018

Abstract excerpt

Abstract Mosaic loss of the Y chromosome (mLOY) is the most commonly reported large structural somatic event. Previous studies have indicated age and cigarette smoking increase the risk of mLOY, but the relationship of other exposures with mLOY and mLOY with disease has not been adequately investigated. We characterized mLOY in a large cohort of 223,338 men from the UK Biobank by scanning for deviations in...

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PMID: 30120341
DOI: 10.1038/s41598-018-30759-1

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