Article

A high aneuploidy supply rate underlies parallel evolution of fluconazole resistance in <i>Saccharomyces cerevisiae</i>

2026-07-17

Abstract excerpt

Copy number variants (CNVs) of ERG11 play a major role in acquisition of resistance to the commonly used azole family of antifungal drugs in many pathogenic yeast species. However, the conditions in which these CNVs arise, and the factors that underlie their emergence and selection in evolving populations, remain poorly understood. Here, we studied the dynamics of de novo CNVs at the ERG11 locus in Saccharomyc...

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Literature Corpus work: 5b80fab0-5629-5edb-bc2e-fa88f398b080
DOI: 10.64898/2026.07.12.738117

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