Article

Aneuploidy promotes transient stress adaptation and metabolic flexibility in the human fungal pathogen <i>Aspergillus fumigatus</i>

2025-09-29

Abstract excerpt

<h4>Summary</h4> Aneuploidy causes genome plasticity and enables adaptive responses that increase stress resistance and facilitate persistence under changing conditions in eukaryotes ranging from fungal pathogens to human cancer cells. Aspergillus fumigatus is a soil-resident mold and the most prevalent etiologic agent of invasive fungal infections globally. Invasive aspergillosis has an alarmingly high mortalit...

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Literature Corpus work: 39876d4b-675a-58b9-9f5e-5955f1ee0dc7
DOI: 10.1101/2025.09.29.679244

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