Article

Analysis of clinical <i>Candida parapsilosis</i> isolates reveals copy number variation in key fluconazole resistance genes

2023-12-14

Abstract excerpt

We used whole-genome sequencing to analyse a collection of 35 fluconazole resistant and 7 susceptible Candida parapsilosis isolates together with coverage analysis and GWAS techniques to identify new mechanisms of fluconazole resistance. Phylogenetic analysis shows that although the collection is diverse, two probable outbreak groups were identified. We identified copy number variation of two genes, ERG11 and C...

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Literature Corpus work: c16be859-20b2-5498-ae06-db6e8cb62ed0
DOI: 10.1101/2023.12.13.571446

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