Article

Switched Fluorogenic CRISPR-tDeg System for RNA Imaging in Living Cells

2025-03-26

Abstract excerpt

<title>Abstract</title> <p>RNA displays significant heterogeneity in its structures, dynamics, and functional roles within cells. CRISPR-based imaging methods provide a powerful approach to visualize RNA molecules in living cells. However, the expression of constitutive fluorescence modules in traditional CRISPR-based tools always produce high background and nonspecific signals. To address these challenges, we de...

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Literature Corpus work: 5b70b286-0466-57c3-a7a7-e32b4f4f5326
DOI: 10.21203/rs.3.rs-6073102/v1

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