Article

The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart

2022-07-05

Abstract excerpt

<h4>ABSTRACT</h4> Long noncoding RNAs (lncRNAs) are emerging as critical regulators of heart physiology and disease, although the studies unveiling their modes-of-action are still limited to few examples. We recently identified pCharme, a chromatin-associated lncRNA whose functional knockout in mice results in defective myogenesis and morphological remodelling of the cardiac muscle. Here, we combined Cap-Analysis...

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Literature Corpus work: 5b0ec4d7-6705-5c12-8afb-c03b51ff9004
DOI: 10.1101/2022.07.05.498800

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