Epigenetic Regulation of Cardiomyocyte Maturation by Arginine Methyltransferase CARM1

Abstract excerpt

BACKGROUND: During the neonatal stage, the cardiomyocyte undergoes a constellation of molecular, cytoarchitectural, and functional changes known collectively as cardiomyocyte maturation to increase myocardial contractility and cardiac output. Despite the importance of cardiomyocyte maturation, the molecular mechanisms governing this critical process remain largely unexplored. METHODS: function on cardiomyocyte...

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