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Polycomb Repressive Complex 1.1 Component, BCOR, Promotes Syncytiotrophoblast Differentiation in Mice and Humans

2024-01-29

Abstract excerpt

Early defects in placenta development are thought to underlie a range of adverse pregnancy conditions including miscarriage, fetal growth abnormalities, preeclampsia, and stillbirth. Differentiating trophoblast stem cells undergo a choreographed allocation of syncytiotrophoblast and extravillous trophoblast cells in response to signaling cues from the developing fetus and the uterine environment. The expression an...

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Literature Corpus work
5abde6dc-2e39-5dd9-a5c2-826a8e9f092c
DOI
10.1101/2024.01.29.577740
Open publication

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Polycomb Repressive Complex 1.1 Component, BCOR, Promotes Syncytiotrophoblast Differentiation in Mice and HumansDOI 10.1101/2024.01.29.577740
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