Article

Cell trajectory modeling identifies a primitive trophoblast state defined by BCAM enrichment

2021-03-28

Abstract excerpt

<h4>ABSTRACT</h4> In early placental development, progenitor cytotrophoblasts (CTBs) differentiate along one of two cellular trajectories: the villous or extravillous pathways. CTBs committed to the villous pathway fuse with neighboring CTBs to form the outer multinucleated syncytiotrophoblast (SCT), while CTBs committed to the extravillous pathway differentiate into invasive extravillous trophoblasts (EVT). Unfo...

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Literature Corpus work: 1eb52329-3565-5062-86b2-ed4e37d59109
DOI: 10.1101/2021.03.27.437349

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