Article

Characterization of Three Somatic Mutations in the 3'UTR of RRAS2 and Their Clinical Implications in Chronic Lymphocytic Leukemia

2023-10-27

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is a hematologic malignancy characterized by progressive accumulation of a rare population of CD5+ B lymphocytes in peripheral blood, bone marrow and lymphoid tissues. CLL exhibits remarkable clinical heterogeneity, with some patients presenting with indolent disease and others progressing rapidly to aggressive CLL. The significant heterogeneity of CLL underscores the importance...

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Literature Corpus work: 5a2c5e96-c6de-5fb9-82ce-d1629723f73a
DOI: 10.20944/preprints202310.1792.v1

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