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Article

Next generation RNA-sequencing in prognostic subsets of chronic lymphocytic leukemia.

American journal of hematology - 1 Jul 2012

Mansouri Larry, Gunnarsson Rebeqa, Sutton Lesley-Ann, Ameur Adam, Hooper Sean D, Mayrhofer Markus, Juliusson Gunnar, Isaksson Anders, Gyllensten Ulf, Rosenquist Richard

Abstract excerpt

Advances in next-generation RNA-sequencing have revealed the complexity of transcriptomes by allowing both coding and noncoding(nc)RNAs to be analyzed. However, limited data exist regarding the whole transcriptional landscape of chronic lymphocytic leukemia(CLL). In this pilot-study, we evaluated RNA-sequencing in CLL by comparing two subsets which carry almost identical or "stereotyped" B-cell receptors with...

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Identifiers

PMID: 22674506
DOI: 10.1002/ajh.23227

Genes

ATM
LPL
MSI2
NOTCH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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