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Article

Characterization of Three Somatic Mutations in the 3'UTR of RRAS2 and Their Inverse Correlation with Lymphocytosis in Chronic Lymphocytic Leukemia.

Cells - 22 Nov 2023

Lacuna Marta, Hortal Alejandro M, Cifuentes Claudia, Gonzalo Tania, Alcoceba Miguel, Bastos Miguel, Bustelo Xosé R, González Marcos, Alarcón Balbino

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is a hematologic malignancy characterized by progressive accumulation of a rare population of CD5+ B-lymphocytes in peripheral blood, bone marrow, and lymphoid tissues. CLL exhibits remarkable clinical heterogeneity, with some patients presenting with indolent disease and others progressing rapidly to aggressive CLL. The significant heterogeneity of CLL underscores the...

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Identifiers

PMID: 38067115
DOI: 10.3390/cells12232687
PMCID: PMC10705375

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of Three Somatic Mutations in the 3'UTR of RRAS2 and Their Inverse Correlation with Lymphocytosis in Chronic Lymphocytic Leukemia.PMID 38067115Read ↗

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