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Article

RNA Editing Alters miRNA Function in Chronic Lymphocytic Leukemia

5 May 2020

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is a high incidence B cell leukemia with a highly variable clinical course, leading to survival times ranging from months to several decades. MicroRNAs (miRNAs) are small non-coding RNAs that regulate the expression levels of genes by binding to the untranslated regions of transcripts. Although miRNAs have been previously shown to play a crucial role in CLL development,...

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PMID: 32380696
DOI: 10.3390/cancers12051159

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